HOMEOSTASIS OF SODIUM IN NEPHROPATHY DOGS UNDER INFUSION OF DOPAMINE

Authors

  • Alexandre Martini Brum FCAV - UNESP/Jaboticabal
  • Marileda Bonafim Carvalho FCAV-UNESP/Jaboticabal
  • Marcy Lancia Pereira FCAV-UNESP/Jaboticabal

DOI:

https://doi.org/10.3738/na.v1i2.276

Keywords:

dopamina, canino, insuficiência renal

Abstract

Dopamine is an endogenous compound widely used in intensive care. It has a broad spectrum of actions on both cardiovascular and urinary system. Increased glomerular filtration rate, renal blood flow and fractional excretion of sodium are expected renal effects in normal individuals, but are little used in veterinary medicine. With the aim to assess the homeostasis of sodium in nephropathy dogs, this study was conducted. Different doses of dopamine were administered in nephropathy dogs. Laboratory evaluations were performed during and after the treatments. The creatinine clearance and fractional excretion of sodium showed dose-dependent increase in healthy dogs. Nephropathy dogs, both dose slightly increased the GFR, but did not alter the fractional excretion of sodium and blood pressure.

Author Biography

  • Alexandre Martini Brum, FCAV - UNESP/Jaboticabal
    Formado em Medicina Veterinária na UFRGS em 2003. Residência em Clínica Médica de pequenos Animais na UNESP/Jaboticabal entre 2003 a 2005. Mestre em Clínica Veterinária pela UNESP/Jaboticabal em 2007. Atualmente doutorando na UNESP/Jaboticabal, na área de nefrologia de pequenos animais e professor da UNIFRAN, nas disciplinas de Çlínica Médica e Terapêutica de Pequenos Animais e LAboratório Clínico Veterinário.

Published

2009-12-08

Issue

Section

Artigos

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